3.4.22.B75 Protease that deconjugates SUMO2 and SUMO3 from targeted proteins, but not SUMO1. Catalyzes the deconjugation of poly-SUMO2 and poly-SUMO3 chains. Has very low efficiency in processing full-length SUMO proteins to their mature forms. SENP67 prefers the LRGG-/- sequence versus the QTGG-/- sequence. - -