2.7.4.14 ATP + UMP = ADP + UDP - - 2.7.4.14 ATP + UMP = ADP + UDP formation of a ternary complex, addition of substrates is random 645141 2.7.4.14 ATP + UMP = ADP + UDP random bi-bi mechanism 645153 2.7.4.14 ATP + UMP = ADP + UDP reaction mechanism is sequential and nonequilibrium in nature, substrates bind to the enzyme in a random order, substrate binding is cooperative 645150 2.7.4.14 ATP + UMP = ADP + UDP reaction proceeds by a sequential mechanism, a ternary complex of the enzyme with both substrates is formed as the central intermediate in the reaction 645148 2.7.4.14 ATP + UMP = ADP + UDP the mechanism is analogous to the phosphoryl transfer mechanism in cAMP-dependent protein kinase that phosphorylates the hydroxyl groups of serine residues 645152