3.1.1.77 glycoprotein - 246554 3.1.1.77 glycoprotein both subunits glycosylated 246549 3.1.1.77 glycoprotein five potential glycosylation sites, one on the small and four on the large subunit 246546 3.1.1.77 glycoprotein glycosylation of the small subunit not essential for activity 246552 3.1.1.77 glycoprotein only three glycosylation sites in large subunit 246554 3.1.1.77 glycoprotein small subunit not glycosylated 246554 3.1.1.77 proteolytic modification proximal tubule cells secrete the pro-enzyme, which can be taken up by bladder cells and processed to the heterodimeric, more enzymatically active, mature enzyme form 665166