1.4.4.2	acetylation	the activity is regulated by sequential posttranslational modifications, including acetylation and polyubiquitination, and reveal critical regulatory mechanisms of glycine metabolism and tumorigenesis. Acetylation of K514 inhibits glycine catabolism and pyrimidine synthesis. In addition, this acetylation of glycine decarboxylase also primes for its K33-linked polyubiquitination and proteasomal degradation, leading to suppression of glycine metabolism and tumorigenesis	765452	
1.4.4.2	proteolytic modification	-	391998	
1.4.4.2	ubiquitination	the activity is regulated by sequential posttranslational modifications, including acetylation and polyubiquitination (K33-linked polyubiquitination), and reveal critical regulatory mechanisms of glycine metabolism and tumorigenesis	765452