3.4.21.46	no modification	no potential N-glycosylation site, no carbohydrate is present in the purified protein	
3.4.21.46	proteolytic modification	profactor D	
3.4.21.46	proteolytic modification	cleavage site for the signal sequence of PoDAK is predicted between Gys24 and Ile25	
3.4.21.46	proteolytic modification	complement factor D is a zymgen with the activation peptide QPRGR at its N-terminus. Mannose-binding lectin-associated serine protease-1 and -3 (Masp 1/3) deficient mice fail convert pro-complement factor D in its active form. Mannose-binding lectin-associated serine protease-1 converts pro-complement factor D in vitro indicating that mannose-binding lectin-associated serine protease-1 (MASP-1) is an essential protease for activating complement factor D