Bos taurus - 639430, 639431, 639433, 639437, 639438, 639442, 639443, 639447, 639448, 639455, 639456, 639457, 639458 Cavia porcellus - 639430 Columba livia - 639445 Felis catus - 639430 Heteropneustes fossilis - 639454 Homo sapiens - 639449, 639451, 639453, 661339, 662596, 672011, 672345, 672557, 672573, 675297, 675306, 696719, 699423, 718693, 718776, 718999, 720467, 733076, 733211 Homo sapiens 21 male and 1 female patient at 0-12 years after heart transplantation, mean age 45.7 years: During the first years after heart transplantation, phenylethanolamine N-methyltransferase mRNA levels are relatively high compared with later years. There is a correlation of phenylethanolamine N-methyltransferase mRNA with years elapsed form heart transplantation (r = -0.56). There is a negative linear correlation between phenylethanolamine N-methyltransferase mRNA and the low frequency band of the power spectrum (r = - 0.47). 677224 Homo sapiens expression plasmid pET17PNMT-his 675288 Homo sapiens female Japanese woman, gene PNMT 697472 Homo sapiens immunohistochemical analysis in normal human medulla shows a expression of phenylethanolamine N-methyltransferase localized to the cytoplasm. All tyrosine hydroxylase-positive cells contain phenylethanolamine N-methyltransferase. All normal human chromaffin cells also strongly express noradrenaline transporter, which is always colocalized with phenylethanolamine N-methyltransferase. Double-labeling experiments on phaeochromocytoma tissue reveals, that the expression of phenylethanolamine N-methyltransferase is variable, ranging from strong to weak to absent. The immunohistochemical detection of phenylethanolamine N-methyltransferase correlates with the presence of adrenaline in all but one sample (but the intensitiy levels do not correlate). In human phaeochromocytomas the expression of the noradrenaline transporter is not consistently co-localized with phenylethanolamine N-methyltransferase. 672987 Homo sapiens recombinant enzyme 661326 Homo sapiens recombinant enzyme with C-terminal His6 tag 661326 Homo sapiens the phenylethanolamine N-methyltransferase inhibitory potency of 3-trifluoromethyl-1,2,3,4-tetrahydroisoquinoline is lower than the of other 1,2,3,4-tetrahydroisoquinolines, some of them show good selectivity due to their extremely low alpha2-adrenoceptor affinity 672582 Macaca mulatta - 639430 Mus musculus - 639450, 673474 Mus musculus C57BL/6 mice 697358 Mus musculus male corticotropin-releasing hormone knockout mice (C57B1/129SV, 20-25 g, approximately 12 weeks old) and wild type mice 673009 Mus musculus mouse pheochromocytoma cell lines 862L and 10/9CRC1 from tumors arising in separate mice with a heterozygous knockout of the neurofibromatosis gene Nf1 673474 Mus musculus C57BL/6 C57BL/6 mice 697358 Oryctolagus cuniculus - 639430, 639432, 639434, 639435, 639436, 639439, 639440, 639441, 639446 Ovis aries - 639444 Rattus norvegicus - 639430, 639433, 639452 Rattus norvegicus male Spargue-Dawley rats 672557 Rattus norvegicus male Sprague-Dawley rats, 260-320 g, approximately 12 weeks old 673009 Rattus norvegicus Wistar rats, 6-12 weeks, either sex. In the immunohistochemistry experiment phenylethanolamine N-methyltransferase demonstrate strong staining in the majority of cells, representing the adrenergic cell population. 672987