2.4.1.245 synthesis maltose, NaCl, K2HPO4 and beef extract are the most significant factors affecting trehalose synthase production in Corynebacterium glutamicum. Trehalose synthase activity increases to 580 U/ml, an approximate 1.76-fold increase over the previous activity (330 U/ml) using an optimized fermentation medium with the main composition maltose (22g/l), beef extract (7.49g/l), NaCl (13.36g/l), K2HPO4(11.33g/l) and peptone (15.00g/l) 736698 2.4.1.245 synthesis synthesis of the trehalase analogue alpha-D-Glc-(1->1)-alpha-D-Glc, that might be effective at inhibiting intestinal brush-order disaccharidases -, 745569 2.4.1.245 synthesis the enzyme is a useful thermostable enzyme particularly for the production of the trehalose analogue containing a mannose that acts as the inhibitor of intestinal sucrase -, 747674 2.4.1.245 synthesis the enzyme may be useful for the regeneration of NDP-alpha-D-glucose from NDP, especially for ADP-alpha-D-glucose from ADP, with trehalose as a glucose resource 723675 2.4.1.245 synthesis trehalose synthase from Pyrococcus horikoshii can be applied to the sugar nucleotide cycling process for the synthesis of functional alpha-galactosyl oligosaccharides, alpha-galactose epitopes and globotriose, using the effective regeneration of UDP-galactose 721854