2.1.1.348 analysis radioactivity-based assays using 3H-S-adenosyl-L-methionine for kinetic characterization of m6A-RNA modifications by METTL3-14 complex and m6A-RNA demethylase ALKBH5. Assay conditions are suitable for screening for ligands in a 384-well format with Z' factors of 0.78 and 0.77, respectively 745396 2.1.1.348 medicine enzyme overexpression is associated with poor prognosis of patients with hepatocellular carcinoma 756898 2.1.1.348 medicine METTL3 expression is elevated in lung adenocarcinoma and promotes growth, survival, and invasion of human lung cancer cells 745757