6.5.1.3	synthesis	efficient synthesis of 5' pre-adenylated DNA	728392	
6.5.1.3	medicine	regulated repression of the enzyme blocks editing, this repression is lethal in bloodforms of the parasite, indicating that editing is essential in the mammalian stage of the life cycle, the editing complex, which is present in all kinetoplastid parasites, may thus be a chemotherapeutic target	653889	
6.5.1.3	synthesis	RNA ligase-mediated method for the efficient creation of large, synthetic RNAs	677096	
6.5.1.3	molecular biology	RNA ligase-mediated rapid amplification of cDNA ends (RLM-RACE)	662976	
6.5.1.3	synthesis	selective isotope labeling of RNA by introducing a labeled RNA segment via a two-step protocol, which uses T4 DNA ligase and T4 RNA ligase 1, and a one-pot protocol, which uses T4 RNA ligase 1 alone. Protection of termini is not required, provided segmentation sites can be chosen such that the segments fold into the target structure or target-like structures and thus are not trapped into stable alternate structures. Labeling protocols are generally applicable to large RNA molecules and can be extended to more than three segments	694461	
6.5.1.3	synthesis	synthesis of oligoribonucleotides with defined sequence	1989	
6.5.1.3	molecular biology	the properties of TS2126 RNA ligase 1 makes it very attractive for processes like adaptor ligation, and single-stranded solid phase gene synthesis	662976