3.4.21.B26	medicine	av endoproteolytic activation is necessary for integrin-mediated adhesion and migration as well as signaling and requires PC5 in vascular smooth muscle cells	673108	
3.4.21.B26	medicine	carotid atherosclerotic lesions obtained by endaterectomy contain PC5, PC5 colocalizes with av integrin	673108	
3.4.21.B26	medicine	crucial role in heart development and in endothelial cells, involved in embryonic bone morphogenesis	673910	
3.4.21.B26	medicine	crucial role in prorenin activation within the adrenal cortex or in HIV gp160 processing in CD4+ cells, major impact on cellular proliferation and on sexual differentiation, involvement in food metabolism	673910	
3.4.21.B26	medicine	PC5 is a potential contributor to the initiation, progression, and complications of atherosclerosis and restenosis, targeting PC5 will likely provide novel anti-atherosclerosis strategies	675490	
3.4.21.B26	medicine	PC5/6 plays a key role for decidualization in human endometrium and its action is necessary for prolactin production from endometrial stromal cells	675051	
3.4.21.B26	medicine	PC5/6A is involved in squamous differentiation of human nasal epithelial cells, possibly through up-regulation of the BMP-2/pSmad1/5/8/p38 signaling pathway, pointing to a potential therapeutic target for the prevention of chronic airway diseases that exhibit squamous metaplasia	752449