3.1.1.41 synthesis bioconversion to and from 7-aminocephalosporanic acid and deacetyl-7-aminocephalosporanic acid. Both are important intermediates in the industrial production of semisynthetic antibiotics 170676 3.1.1.41 synthesis enzyme reaction products deacetyl cephalosporins are a highly valuable starting material for producing semisynthetic beta-lactam antibiotics -, 677538 3.1.1.41 synthesis high-level production of cephalosporin C deacetylase by recombinant Escherichia coli. The CAH activity produced increases approximately 3 times after systematic optimization. Using glycerol feeding with pH control, an effective fermentation process for recombinant CAH production is established in a 7.0 L fermenter -, 749834 3.1.1.41 synthesis one-pot bi-enzyme catalyzed procedure for industrial conversion of cephalosporin C to deacetyl-7-aminocephalosporanic acid. Use of immobilized cephalosporin C acylase and immobilized cephalosporin C deacetylase give a yield of 78.39% deacetyl-7-aminocephalosporanic acid achieved in 30 min in a single reactor under the optimized conditions. The half-time of immobilized cephalosporin C deacetylase is approximately 18 h 749837 3.1.1.41 synthesis production of 7-aminocephalosporanic acid, which is an intermediate for semi-synthetic penicillins and cephalosporins 660484 3.1.1.41 synthesis production of 7-aminocephalosporanic acid, which is an intermediate for semisynthetic penicillins and cephalosporins -, 660484 3.1.1.41 synthesis production of deacetyl 7-aminocephalosporanic acid as precursor for the synthesis of cefcapene pivoxil hydrochloride (Flomox) -, 671502 3.1.1.41 synthesis synthesis of deacetylcephalosporin C directly in a fermentation process 675216