2.6.1.16	analysis	assay of synthase and hemisynthase activities of glucosamine-6-phosphate synthase by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry, allowing determination of both hemisynthase and synthase parameters from a single assay kinetic experiment	737433	
2.6.1.16	analysis	development of an assay for glucosamine 6-phosphate synthase that measures the production of glucosamine 6-phosphate by either following the consumption of acetyl-CoA spectrophotometrically at 230 nm or quantifying the free thiol with 5,5'-dithio-bis(2-nitrobenzoic acid), i.e. Ellman’s reagent in a discontinuous manner. Simple assay method, which can be adapted to 96-well microtiter plate format	684404	
2.6.1.16	medicine	GFPT1 mutations in congenital myasthenic syndrome patients do not appear to compromise global N-glycosylation in muscle cells. The N-glycomes of myoblasts and myotubes derived from healthy controls, GFPT1 patients, and patients with other muscular diesease exhibit broadly similar levels of branching and relative abundances of bi-, tri-, and tetra-antennary N-glycans. Although some differences are observed in the relative abundances of some of the N-glycan constituents, these variations are modest and are not confined to the GFPT1 samples	737811	
2.6.1.16	medicine	hypoxia induces gene expression in phagocyte	674058	
2.6.1.16	medicine	mean glutamine:fructose 6-phosphate amidotransferase activity is significantly higher in diabetic compared to control subjects. Plasma levels of diabetic patients also exhibit increased lipid peroxidation and protein carbonylation. Glutamine:fructose 6-phosphate amidotransferase activity is positively correlated with glutamine:fructose 6-phosphate amidotransferase mRNA, HbA1c, insulin resistance, postprandial plasma glucose and levels of thiobarbituric acid reactive substances and protein carbonyl content	686132	
2.6.1.16	medicine	target for antifungal agents	671032	
2.6.1.16	synthesis	the enzyme is useful in bioproduction of N-acetylglucosamine (GlcNAc), a nutraceutical that has various applications in healthcare	-, 756261