4.2.1.46 analysis the highly conserved sequence of the dTDP-glucose-4,6-dehydratase gene is used to explore the Streptomyces tenebrarius H6 tabromycin/kanamycin biosynthetic gene cluster 4.2.1.46 analysis an absorbance-based microtiter plate assay is developed for RmlB activity. It can be used for high-throughput screening of RmlB inhibitors 4.2.1.46 pharmacology the enzyme is essential to mycobacterial growth and is not found in humans, therefore, it is a potential target for developing new anti-tuberculosis drugs 4.2.1.46 synthesis hemo-enzymatic syntheses of artificial and naturally occuring deoxysugars 4.2.1.46 synthesis Synthesis of dTDP-6-deoxy-4-keto-D-glucose (intermediate for synthesis of activated deoxysugars)