3.2.1.108	food industry	the enzyme is used for the production of dairy products	732766	
3.2.1.108	medicine	absorption of quercetin-3-glucoside requires hydrolysis by the enzyme, absorption of quercetin-4’-glucoside requires both an interaction with sodium-dependent glucose transporter and hydrolysis by the enzyme	654552	
3.2.1.108	medicine	among 107 milk-drinking Somali camel-herders from Ethiopia, eight polymorphic sites are identified in the enhancer sequence in an intron of a neighboring gene MCM6 which modulates lactase transcription in vitro. -13915*G and -13907*G are each significantly associated with lactase persistence. Allele -14009*G has borderline association with lactase persistence, but loses significance after correction for multiple testing. Sequence diversity of the enhancer is significantly higher in the lactase persistent members of this and a second cohort compared with non-persistent members of the two groups	709567	
3.2.1.108	medicine	analysis of sequence variants of lactase persistence/lactase non-persistence LP/LNP in subjects originating from Northern Russia. The prevalence of the -13910C/C genotype among 148 patients was 28.4%. A G to A variant residing 13914 bp upstream from the LCT gene, -13914G/A, was identified in one participant carrying the -13910C/C genotype. The -13914G/A variant in heterozygous state is associated with increased lactase activity, suggesting that the increased lactase activity is most likely to be associated with the -13914G/A variant	710555	
3.2.1.108	medicine	C/T-13910 cis-acting regulatory variant located around 14 kb upstream of lactase gene completely correlates with lactase phenotype in Indian children. The genetic testing for the C/T -13910 variant may be helpful in the diagnosis of adult-type hypolactasia in Indian children	714761	
3.2.1.108	medicine	enzyme plays a major role in metabolism of glycosilated phytochemicals	657409	
3.2.1.108	medicine	findings facilitate genetic testing and enable genetic counseling for congential lactase deficiency, CLD	683038	
3.2.1.108	medicine	in irritable bowel syndrome, IBS, patients, genotyping of C/T_13910 and G/A_22018 polymorphisms predicts gastrointestinal symptoms after lactose ingestion and are a diagnostic tool for lactose intolerance	683371	
3.2.1.108	medicine	the C allele of the T-13910C polymorphism causing lactose intolerance is associated with lower dietary calcium intake and serum calcium levels but not with bone mineral density or fractures. The associations observed with height and vertebral area were the result of population stratification	709206	
3.2.1.108	medicine	the T/G-13915 variant is the founder mutation of lactase persistence, the result has implications for genetic testing of adult-type hypolactasia	683765	
3.2.1.108	medicine	the use of new substrates for the measurement of lactase activity provides a new method for the noninvasive diagnosis of hypolactasia	683231	
3.2.1.108	pharmacology	BALB/c mouse LPH cDNA provides a necessary foundation for study of the biological function and regulatory mechanism of the lactose intolerance in mice	-, 683224