2.8.3.16 environmental protection bacterial oxalate-degrading function, microbiological processes are considered as the main oxalate sinks in natural environments, in soil oxalate from fungi, plant root exudates and decaying plant tissues display powerful metal chelating properties. Oxalate takes part in plant nutrition status by increasing the availability of phosphate and other poorly soluble micro-nutriments, through its ability to complex and remove excess metal cations. It also plays an important role in the detoxification of heavy metals in the vicinity of plant roots. -, 693608 2.8.3.16 medicine bacterial oxalate-degrading function, in humans an accumulation of oxalic acid can result in a number of pathologic conditions, including hyperoxaluria, urolithiasis, renal failure, cardiomyopathy and cardiac conductance disorders -, 693608 2.8.3.16 medicine gene therapy of hyperoxaluria 692677 2.8.3.16 medicine potential therapeutic use in managing oxalate kidney stone disease in humans -, 692373 2.8.3.16 molecular biology use of the frc gene as template for PCR to detect oxalotrophic bacteria -, 693608