2.3.1.B41 medicine PfSir2A inhibitors may have therapeutic value in malaria treatment 2.3.1.B41 medicine SIRT6 and its downstream signaling can be targeted in Alzheimer's disease and age related neurodegeneration 2.3.1.B41 medicine SIRT6 as a potential therapeutic target to prevent astrocyte-mediated motor neuron death in amyotrophic lateral sclerosis (ALS) 2.3.1.B41 medicine small molecule activators for the human sirtuins Sirt1-7 are sought as chemical tools and potential therapeutics, such as for cancer 2.3.1.B41 medicine the enzyme is a potential therapeutic target for therapy of cancer and other metabolic diseases 2.3.1.B41 medicine the enzyme is a therapeutic target for ovarian cancer therapy 2.3.1.B41 medicine the oncogenic role of SIRT6 in skin cancer suggest SIRT6 as a potential target for developing chemopreventive strategies to reduce the skin cancer