5.3.2.1 (4-Hydroxyphenyl)pyruvate - 5.3.2.1 keto-(4-hydroxyphenyl)pyruvate - 5.3.2.1 keto-phenylpyruvate - 5.3.2.1 additional information role in the biosynthesis of thyroxine 5.3.2.1 additional information important immunoregulatory molecule with a unique ability to suppress the anti-inflammatory effects of glucocorticoids 5.3.2.1 additional information the enzymatic activity of macrophage migration inhibitory factor does not play a role in its migration inhibiting properties. Macrophage migration inhibitory factor is an inhibitor of the random migration of monocytes and macrophages and has since been proposed to have a number of immune and catalytic functions, macrophage migration inhibitory factor is an inhibitor of monocyte chemoattractant protein 1-induced chemotaxis of human peripheral blood monocytes 5.3.2.1 additional information the enzyme is chemotactic for human monocytes and activates them to produce IL-8, TNF-alpha and endogenous MIF 5.3.2.1 additional information MIF is a homotrimeric multifunctional proinflammatory cytokine. It also shows dopachrome tautomerase activity. Binding of MIF to its receptor, CD74, overview 5.3.2.1 additional information the MIF protein is multifunctional, exhibiting besides its tautomerase activity, e.g. also L-dopachrome isomerase activity, EC 5.3.3.12, and thioredoxin-like function, or its cytokine function, overview 5.3.2.1 Phenylpyruvate -