4.4.1.21 additional information the enzyme is involved in one of the the quorum sensing systems that function in parallel to control the density-dependent expression of the luciferase structural operon luxCDABE. Each system is composed of a sensor, sensor I or sensor 2, and its cognate autoinducer, AI-1 or AI-2. LuxS has a role in the enzymatic synthesis of AI-2 4.4.1.21 additional information growth phase regulation of flaA expression in Helicobacter pylori is luxS-dependent 4.4.1.21 additional information LuxS is related on the one hand to down-regulation of competence, and on the other hand to attenuation of autolysis in cultures entering stationary phase. The impact of LuxS on competence, but not on autolysis, involves cel-cell communication 4.4.1.21 additional information the LuxS/AI-2 (autoinducer 2) system does not appear to contribute to the overall fitness of Staphylococcus aureus RN6390B during intracellular growth in epithelial cells 4.4.1.21 additional information LuxS catalyzes production of the AI-2 autoinducer molecule for a second quorum sensing system 4.4.1.21 additional information LuxS catalyzes the last step in the production of autoinducer-2 4.4.1.21 additional information LuxS is functional in the autoinducer-2-mediated quorum sensing and may regulate different behaviors including biofilm formation and virulence 4.4.1.21 additional information LuxS is involved in the activated methyl cycle and influences biofilm formation 4.4.1.21 additional information LuxS is required for normal biofilm development 4.4.1.21 additional information LuxS plays an important role in the regulation of motility and flagella biogenesis