4.2.1.1 CO2 + H2O - 4.2.1.1 CO2 + H2O periplasmic alpha-carbonic anhydrase activity of Helicobacter pylori is essential for acid acclimation 4.2.1.1 H2CO3 - 4.2.1.1 H2CO3 essential physiological function is to catalyze the hydration of carbon dioxide and the backreaction, the dehydration of bicarbonate 4.2.1.1 H2CO3 plays a role in the hypersensitive defense response 4.2.1.1 H2CO3 plays a role in various physiological functions, including interconversion between CO2 and HCO3- in intermediary metabolism, facilitated diffusion of CO2, pH homeostasis and ion transport 4.2.1.1 H2CO3 CsoSCA converts HCO3- to CO2 for use in carbon fixation by ribulose-bisphosphate carboxylase/oxygenase 4.2.1.1 additional information carbonic anhydrase I, II and III are constitutive enzymes 4.2.1.1 additional information carbonic anhydrase 2 is induced by high CO2 concentration, carbonic anhydrase 1 is induced by low and high CO2 concentration 4.2.1.1 additional information carbonic anhydrase IV is possibly responsible for HCO3- secretion, the cytoplasmic form of carbonic anhydrase II is believed to play a role in pH regulation near apical ionic channels of the near apical carbonic anhydrase IV