3.6.1.23 dCTP + H2O - 3.6.1.23 dUTP + H2O - 3.6.1.23 dUTP + H2O removes dUTP from the nucleotide triphosphate pool and therefore prevents the incorporation of uracil into the DNA 3.6.1.23 dUTP + H2O removes dUTP from the nucleotide triphosphate pool and therefore prevents the incorporation of uracil into the DNA, essential for replication and cell survival 3.6.1.23 dUTP + H2O removes dUTP from the nucleotide triphosphate pool and therefore prevents the incorporation of uracil into the DNA, provides substrate for dTTP synthesis 3.6.1.23 dUTP + H2O removes dUTP from the nucleotide triphosphate pool and therefore prevents the incorporation of uracil into the DNA, provides the substrate thymidylate synthase and is therefore essential for the synthesis of dTTP 3.6.1.23 dUTP + H2O biological roles and functions of dUTPase-related proteins and domains, overview 3.6.1.23 dUTP + H2O dUMP is required for biosynthesis of dTTP, overview 3.6.1.23 dUTP + H2O the enzyme is essential in the lytic cycle of the virus 3.6.1.23 dUTP + H2O the enzyme prevents incorporation of uracil into DNA by strict regulation of the cellular dUTP to dTTP ratio, developmental regulation of the isozymes at mRNA and protein levels