3.5.1.11 benzylpenicillin + H2O - 3.5.1.11 benzylpenicillin + H2O highly specific 3.5.1.11 additional information other natural penicillins 3.5.1.11 additional information intracellular proteolysis in the cytoplasm is one of the important steps that limit the yield of active penicillin amidase from the translational product pre-pro-peniciliin amidase. Glucose and temperature are important parameters, determining the degradation rate of the proteolytically sensitive pre-pro-penicillin amidase 3.5.1.11 additional information autoproteolytic processing of the alpha and beta subunit 3.5.1.11 additional information penicillin acylase is able to both hydrolyze and synthesize beta-lactam antibiotics 3.5.1.11 penicillin + H2O - 3.5.1.11 penicillin dihydroF + H2O substrate of immobilized enzyme 3.5.1.11 penicillin F + H2O substrate of immobilized enzyme 3.5.1.11 penicillin G + H2O -