3.4.23.51	precursor of the large subunit of hydrogenase 3 + H2O	-	
3.4.23.51	precursor of the large subunit of hydrogenase 3 + H2O	i.e. HycE	
3.4.23.51	precursor of the large subunit of hydrogenase 3 + H2O	HycI involved in the C-terminal processing of HycE, the large subunit of the hydrogenase 3 from Escherichia coli	
3.4.23.51	precursor of the large subunit of hydrogenase 3 + H2O	HycI is an endopeptidase that is responsible for the C-terminal cleavage of the large subunit of hydrogenase 3 in Escherichia coli (UniProt: A1AER2)	
3.4.23.51	precursor of the large subunit of hydrogenase 3 + H2O	the final step of maturation of [NiFe]-hydrogenases involves the activity of an endopeptidase which removes an oligopeptide from the C-terminus of the large subunit. The proteolytic maturation is followed by a conformational change, closing of the metal centre, its assembly with the small hydrogenase subunit and finally in the appearance of enzyme activity. HycI is specific for hydrogenase 3 maturation