3.4.22.6	2,4-dichlorocyclohexan-1-one + cyclohexanone	yield: 43%, 80:20 anti/syn, ee (anti): 81%	
3.4.22.6	2,6-dichlorocyclohexan-1-one + cyclohexanone	yield: 39%, 99:01 anti/syn, ee (anti): 58%	
3.4.22.6	2-chlorocyclohexan-1-one + cyclohexanone	yield: 30%, 86:14 anti/syn, ee (anti): 79%	
3.4.22.6	2-nitrocyclohexan-1-one + cyclohexanone	yield: 24%, 87:13 anti/syn, ee (anti): 82%	
3.4.22.6	3-chlorocyclohexan-1-one + cyclohexanone	yield: 32%, 65:35 anti/syn, ee (anti): 93%	
3.4.22.6	3-nitrocyclohexan-1-one + cyclohexanone	yield: 41%, 87:13 anti/syn, ee (anti): 86%	
3.4.22.6	4-bromocyclohexan-1-one + cyclohexanone	yield: 29%, 81:19 anti/syn, ee (anti): 84%	
3.4.22.6	4-chlorocyclohexan-1-one + cyclohexanone	yield: 47%, 69:31 anti/syn, ee (anti): 75%	
3.4.22.6	4-cyanobenzaldehyde + cyclohexanone	catalytic activity and stereoselectivity of chymopapainare influenced by different media. Best catalytic activity and moderate stereoselectivity in DMSO (yield: 50%, anti/syn ratio 55:45, ee(anti): 40%), best enantioselectivity in CH2Cl2 (yield: 18%, anti/syn ratio: 61:39, ee(anti): 79%)	
3.4.22.6	4-cyanobenzaldehyde + cyclohexanone	solvent: water/MeCN. The water content greatly affects the activity and selectivity of chymopapain for the aldol reaction. The best enantioselectivity and diastereoselectivity at the water content of 0.12 (water/MeCN, v/v), which give the product in a yield of 28% with 73:27 (anti/syn ratio) and 77% ee (for anti isomer). Best enzyme activity at the water content of 0.15, which give a yield of 32% with lower selectivity