3.4.21.37 alpha1-PI + H2O important antiprotease of the lung, enzyme reduces the lungs’ primary protection against proteolysis 3.4.21.37 annexin 1 + H2O annexin 1 is externalized and truncated upon adhesion of polymorphonuclear leukocytes to endothelial cells, annexin 1 participates in regulating leukocyte emigration into inflamed tissue through N-terminal peptides generated at inflammatory sites, overview 3.4.21.37 Antithrombin III + H2O degradation 3.4.21.37 BP180/type XVII collagen + H2O neutrophil elastase degrades recombinant mouse BP180 within the immunodominant extracellular domain at amino acid positions 506 and 561 3.4.21.37 coagulation factor V + H2O - 3.4.21.37 coagulation factor VIII + H2O - 3.4.21.37 coagulation factor XI + H2O - 3.4.21.37 coagulation factor XIII + H2O - 3.4.21.37 Collagen + H2O - 3.4.21.37 Collagen + H2O degradation