3.1.3.106 1-oleoyl-sn-glycerol 3-phosphate + H2O - 3.1.3.106 lysophosphatidate + H2O best substrate 3.1.3.106 lysophosphatidic acid + H2O - 3.1.3.106 additional information LPP is involved in regulation of bioactive lipids acting in signalling pathways, overview, LPP-1 regulates the lysophosphatidic acid-induced calcium release, NF-kappaB activation and interleukin-8 secretion in epithelial cells 3.1.3.106 additional information LPP is involved in regulation of bioactive lipids acting in signalling pathways, overview, LPP-1 regulates the lysophosphatidic acid-induced calcium release, NF-kappaB activation and interleukin-8 secretion in human bronchial epithelial cells 3.1.3.106 additional information no substrate: glycerol 3-phosphate. Activity increases with the length of acyl chain to a peak value on 14:0-lysophosphatidic acid. Activity gradually decreases, when the substrate length is increased above the optimal 14:0-lysophosphatidic acid 3.1.3.106 myristoyl-sn-glycerol3-phosphate + H2O best substrate 3.1.3.106 oleoyl-sn-glycerol 3-phosphate + H2O - 3.1.3.106 oleoyl-sn-glycerol 3-phosphate + H2O about 2fold the activity of stearoyl-sn-glycerol 3-phosphate 3.1.3.106 palmitoyl-sn-glycerol 3-phosphate + H2O -