2.7.7.22	GDP + alpha-D-mannose 1-phosphate	-	
2.7.7.22	GDP + alpha-D-mannose 1-phosphate	GMP catalyzes the synthesis of GDP-mannose, an important step in the formation of all guanosine-containing sugar nucleotides in plants. The GDP-mannose produced by the enzymatic action of GMP plays vital roles in both prokaryotes and eukaryotes, overview. The enzyme activity is correlated to the amount of ascorbic acid, overview	
2.7.7.22	GDPmannose + phosphate	-	
2.7.7.22	GDPmannose + phosphate	reverse reaction involved in synthesis of the compatible solute alpha-mannosylglycerate	
2.7.7.22	additional information	GDP-mannose, the mannose donor, required for the main cryptococcal virulence factor, a polysaccharide capsule that surrounds the cell, is produced in the cytosol by the sequential actions of phosphomannose isomerase, phosphomannomutase, and GDP-mannose pyrophosphorylase. Cryptococcus neoformans is a fungal pathogen that is responsible for life-threatening disease, particularly in the context of compromised immunity	
2.7.7.22	additional information	GMP is an important enzyme in the Smirnoff-Wheeler’s pathway for the biosynthesis of ascorbic acid in plants	
2.7.7.22	additional information	the essential enzyme plays a major role in the Smirnoff-Wheeler’s L-ascorbic acid biosynthetic pathway in plants