2.3.3.10 acetyl-CoA + acetoacetyl-CoA + H2O - 2.3.3.10 acetyl-CoA + acetoacetyl-CoA + H2O cytosolic synthase catalyzes the second step of cholesterogenesis from acetyl-CoA 2.3.3.10 acetyl-CoA + acetoacetyl-CoA + H2O produces a key intermediate in steroidogenic and ketogenic metabolic pathways 2.3.3.10 acetyl-CoA + acetoacetyl-CoA + H2O isopentenyl diphosphate biosynthesis 2.3.3.10 acetyl-CoA + acetoacetyl-CoA + H2O mitochondrial enzyme is involved in the synthesis of acetoacetate, cytoplasmic enzyme in that of mevalonate 2.3.3.10 acetyl-CoA + acetoacetyl-CoA + H2O commited step in the pathways for isoprenoid, cholesterol and ketone body production, cytosolic isoform involved in isoprenoid/cholesterol biosynthesis 2.3.3.10 acetyl-CoA + acetoacetyl-CoA + H2O mitochondrial enzyme of liver functions in ketogenesis, its cytoplasmic counterpart participates in cholesterogenesis 2.3.3.10 acetyl-CoA + acetoacetyl-CoA + H2O first committed step in isoprenoid biosynthesis 2.3.3.10 acetyl-CoA + acetoacetyl-CoA + H2O pathway converting acetyl-CoA to ketone bodies 2.3.3.10 acetyl-CoA + acetoacetyl-CoA + H2O synthesis of isoprenes and steroids