2.3.1.157 acetyl-CoA + alpha-D-galactosamine 1-phosphate - 2.3.1.157 acetyl-CoA + alpha-D-glucosamine 1-phosphate - 2.3.1.157 acetyl-CoA + alpha-D-glucosamine 1-phosphate because the ST0452 protein is capable of catalyzing the last two reactions (Ec 2.3.1.157 and EC 2.7.7.23 (UDP-N-acetylglucosamine diphosphorylase)) of the bacteria-type four-step biosynthesis pathway of UDP-GlcNAc from fructose 6-phosphate, the ST0452 protein plays an important role for the bacteria-type UDP-GlcNAc biosynthesis pathway in this archaeon 2.3.1.157 acetyl-CoA + alpha-D-glucosamine 1-phosphate the enzyme is involved in the cell wall biosynthesis of Gram-negative organisms 2.3.1.157 acetyl-CoA + alpha-D-glucosamine 1-phosphate the enzyme is responsible for the final two steps of the synthesis of UDP-N-acetylglucosamine, which is an essential precursor of peptidoglycan 2.3.1.157 D-glucosamine 1-phosphate + acetyl-CoA - 2.3.1.157 D-glucosamine 1-phosphate + acetyl-CoA the bifunctional enzyme also possesses the activity of EC 2.7.7.23, UDP-N-acetylglucosamine diphosphorylase and performs the last two steps in the synthesis of UDP-N-acetylglucosamine 2.3.1.157 D-glucosamine 1-phosphate + acetyl-CoA the bifunctional enzyme also possesses the activity of EC 2.7.7.23, UDP-N-acetylglucosamine diphosphorylase and performs the last two steps in the synthesis of UDP-N-acetylglucosamine, which is an essential precursor in bacterial cell wall biosynthesis 2.3.1.157 D-glucosamine 1-phosphate + acetyl-CoA the bifunctional enzyme also possesses the activity of EC 2.7.7.23, UDP-N-acetylglucosamine diphosphorylase and performs the last two steps in the synthesis of UDP-N-acetylglucosamine, which is an essential precursor in both the peptidoglycan and the lipopolysaccharide metabolic pathway 2.3.1.157 additional information GlmU also catalyzes the reaction of the N-acetylglucosamine-1-phosphate uridyltransferase, EC 2.7.7.23, catalyzing the synthesis of UDP-GlcNAc from GlcNAc-1-phosphate and UTP