2.1.1.360	3 S-adenosyl-L-methionine + a [histone H3]-L-lysine79	overall reaction	
2.1.1.360	additional information	AF10 bound to the enzyme simultaneously senses unmodified histone H3 lysine 27 via its PHD finger-Zn knuckle-PHD finger domain and enables the enzyme to methylate histone H3 at lysine 79. Knockout embryos, lacking Af10, have reduced [histone H3]-N6-methyl-L-lysine79 in developing nasal processes and reduced expression of AP2alpha, a gene required for cranial neural crest cell development	
2.1.1.360	S-adenosyl-L-methionine + a [histone H3]-L-lysine79	-	
2.1.1.360	S-adenosyl-L-methionine + a [histone H3]-N6,N6-dimethyl-L-lysine79	-	
2.1.1.360	S-adenosyl-L-methionine + a [histone H3]-N6-methyl-L-lysine79	-	
2.1.1.360	S-adenosyl-L-methionine + histone L-lysine	-	
2.1.1.360	S-adenosyl-L-methionine + [histone H3]-L-lysine79	-	
2.1.1.360	S-adenosyl-L-methionine + [histone H3]-N6-methyl-L-lysine79	-