1.4.1.3 2-oxoglutarate + NH3 + NAD(P)H + H+ - 1.4.1.3 L-glutamate + H2O + NAD(P)+ enzyme for the main route for ammonia assimilation at low concentrations of ammonia 1.4.1.3 L-glutamate + H2O + NAD(P)+ - 1.4.1.3 L-glutamate + H2O + NAD+ - 1.4.1.3 L-glutamate + H2O + NADP+ - 1.4.1.3 additional information the similarity in relative activation when both cofactors are present, combined with consistently greater GDH product formation from equimolar NADH than with NADPH, does not support the idea that there is a preferential utilization of NADPH by bovine GDH