1.1.99.2	(S)-2-hydroxyglutarate + acceptor	-	
1.1.99.2	(S)-2-hydroxyglutarate + acceptor	enzyme deficiency might be the cause of L-2-hydroxyglutaric aciduria	
1.1.99.2	(S)-2-hydroxyglutarate + FAD	enzyme deficiency might be the cause of L-2-hydroxyglutaric aciduria	
1.1.99.2	(S)-2-hydroxyglutarate + NAD+	-	
1.1.99.2	L-2-hydroxyglutarate + FAD	-	
1.1.99.2	L-2-hydroxyglutarate + NAD+	-	
1.1.99.2	additional information	high levels of the enzyme is produced at the late stage of cultivation in the presence of citrate and with limited aeration	
1.1.99.2	additional information	mutations (K81E, E176D, DELTA-exon9) found in patients with L-2-hydroxyglutaric aciduria supress L-2-hydroxyglutarate dehydrogenase activity. L-2-hydroxyglutartic aciduria is due to a deficiency in L-2-hydroxyglutarate dehydrogenase