5.1.3.37 additional information effect of ManC5-Es on alginate structures, overview. Alginate in brown algae is first formed as a polysaccharide chain containing mannuronic acid residues only. These are subsequently transformed by the ManC5-E into guluronic acid residues, generating distinct patterns arranged in regions of MM-, GG- and MG-blocks (beta-D-mannuronic acid (M) and alpha-L-guluronic acid (G) residues). Patterns containing large stretches of adjacent guluronic acid residues (GG-blocks) form structured interchain associations in the presence of Ca2+ ions. These interchain junctions have the so-called egg-box conformation and are responsible for the gelling properties of alginate and cell-wall strengthening 5.1.3.37 additional information effect of ManC5-Es on alginate structures, overview. Alginate in brown algae is first formed as a polysaccharide chain containing mannuronic acid residues only. These are subsequently transformed by the ManC5-E into guluronic acid residues, generating distinct patterns arranged in regions of MM-, GG- and MG-blocks (beta-D-mannuronic acid (M) and alpha-L-guluronic acid (G) residues). Patterns containing large stretches of adjacent guluronic acid residues (GG-blocks) form structured interchain associations in the presence of Ca2+ ions. These interchain junctions have the socalled egg-box conformation and are responsible for the gelling properties of alginate and cell-wall strengthening 5.1.3.37 [mannuronan]-beta-D-mannuronate -