3.5.4.4	2'-deoxyadenosine + H2O	-	
3.5.4.4	5'-methylthioadenosine + H2O	-	
3.5.4.4	adenosine + H2O	-	
3.5.4.4	adenosine + H2O	ADA, nucleotide metabolism	
3.5.4.4	5'-methylthioadenosine + H2O	adenosine deaminase has a secondary function in recycling methylthiopurines from the polyamine biosynthetic pathway	
3.5.4.4	additional information	adenosine deaminase inhibition enhances the efficiency of signal transduction and inotropic response mediated by A1 adenosine receptor in hyperthyroid guinea pig atrium via elevated intracellular adenosine levels, overview	
3.5.4.4	adenosine + H2O	adenosine deaminase is involved in purine metabolism and is a key enzyme for the control of the cellular levels of adenosine	
3.5.4.4	adenosine + H2O	adenosine deamination is involved in the essential pathway of purine salvage in Plasmodium falciparum, and inhibition of purine salvage results in parasite death	
3.5.4.4	additional information	adenosine modulates the immune system and inhibits inflammation via reduction of cytokine biosynthesis and neutrophil functions, enzyme inhibition reduces inflammation in experimental colitis, overview	
3.5.4.4	adenosine + H2O	isozyme ADA2 is important in lymphocyte activation, and may be active in sites of inflammation and during hypoxia and in areas of tumor growth with elevated adenosine levels and acidic pH, overview