3.5.3.1	L-arginine + H2O	-	
3.5.3.1	L-arginine + H2O	arginase catalyzes the first committed step in the biosynthesis of polyamines	
3.5.3.1	L-arginine + H2O	arginase competes with nitric oxide synthases for L-arginine as the common substrate	
3.5.3.1	additional information	arginase II is constitutively expressed in the airways of normal mice, whereas arginase I is undetectable in normal airways, while its expression is increased in airways of mice exposed to ovalbumin	
3.5.3.1	additional information	complex regulation of natural killer cell functions by arginine availability	
3.5.3.1	L-arginine + H2O	enzyme is involved in acid resistance and inhibits host nitric oxide production	
3.5.3.1	L-arginine + H2O	enzyme is involved in net production of ornithine, a precursor of polyamines, glutamate, and proline, enzyme is also involved in regulation of nitric oxide biosynthesis by modulating arginine availability for nitric oxide synthase	
3.5.3.1	L-arginine + H2O	enzyme is involved in regulating L-arginine bioavailability to NO synthase in human penile corpus cavernosum smooth muscle, and in clitoral corpus cavernosum and vagina, enzyme plays a role in both female and male sexual arousal	
3.5.3.1	L-arginine + H2O	enzyme is involved in regulation of nitric oxide biosynthesis by modulating arginine availability for nitric oxide synthase	
3.5.3.1	additional information	enzyme may be involved in cellular proliferation in atherosclerosis, inhibiton of enzyme expression by 17beta-estradiol as mechanism in attenuating atherogenensis