3.4.21.92	additional information	-	
3.4.21.92	central competence regulator sigmax + H2O	adaptor protein MecA ultimately targets sigmaX for its degradation by the ClpCP protease in an ATP-dependent manner	
3.4.21.92	additional information	ClpP associates with ClpX or ClpA to form the AAA+ ClpXP or ClpAP proteases	
3.4.21.92	additional information	ClpP binds to AAA+ ATPase/unfoldase, ClpA or ClpX	
3.4.21.92	additional information	ClpP is present in a wide range of prokaryotic and eukaryotic cells and is highly conserved in plant chloroplasts	
3.4.21.92	additional information	ClpP linked to many activities, including sporulation, cell competence, stress tolerance and regulation of gene expression	
3.4.21.92	additional information	ClpP requires association with ClpA or ClpX to unfold and thread protein substrates through the axial pore into the inner chamber where degradation occurs	
3.4.21.92	additional information	ClpXP appears to be involved in plasmid maintenance and in phage Mu virulence	
3.4.21.92	additional information	enzyme complex ClpPRS consisting of five ClpP protease molecules, four nonproteolytic ClpR molecules, and two associated ClpS molecules, is central to chloroplast biogenesis, thylakoid protein homeostasis, and plant development	
3.4.21.92	additional information	enzyme is required for release of autolysin A and pneumolysin. In vivo, it is required for growth of pneumococcus in the lungs and blood in a murine model of disease