3.1.21.4 DNA + H2O - 3.1.21.4 DNA + H2O primary function is the inactivation of foreign DNA invading bacteria 3.1.21.4 DNA + H2O sequence-specific endonucleolytic digestion of infecting DNA 3.1.21.4 DNA containing F5dC + H2O perfectly hydrolyzes the DNA containing 5-fluoro-dC 3.1.21.4 DNA containing F5dU + H2O perfectly hydrolyzes the DNA containing 5-fluoro-dU 3.1.21.4 double-stranded DNA + H2O cleavage by EcoRI is staggered, producing fragments with 4-nucleotide single-stranded overhangs, recognition sequence is GAATTC 3.1.21.4 double-stranded DNA + H2O cleavage by EcoRV is staggered, producing fragments with 4-nucleotide single-stranded overhangs, recognition sequence is GATATC 3.1.21.4 double-stranded DNA + H2O - 3.1.21.4 double-stranded DNA + H2O the enzyme recognizes the sequence 5'-Pu*CCGGPy and cleaves it as indicated by the star 3.1.21.4 double-stranded DNA + H2O LmoJ3 recognizes GCNGC