2.4.1.117 additional information enzyme is involved in the biosynthesis of the lipid-linked oligosaccharides that are precursors of N-linked glycoproteins 2.4.1.117 additional information synthesis of dolichyl D-glucosyl phosphate, a glucosyl donor in the formation of lipid-linked core oligosaccharides 2.4.1.117 additional information mutations in wollknäuel, a UDPglucose:dolichyl-phosphate glucosyltransferase involved in N-linked protein glycosylation, disrupts Drosophila embryo development by affecting the expression of a few key gene regulators. Reduced glycosylation efficiency in wol mutant embryos triggers the unfolded protein response. As a result, phosphorylation of eIF2a is increased 2.4.1.117 UDP-glucose + dolichyl phosphate -