2.3.1.B41 additional information the enzyme preferentially hydrolyzes long-chain fatty acyl groups over acetyl groups in vitro 2.3.1.B41 additional information acetylation of nicotinamide phosphoribosyltransferase, i.e. NAMPT, on residue K53 by SIRT6 2.3.1.B41 additional information SIRT6 deacetylates Beclin-1 in HCC cells 2.3.1.B41 additional information SIRT6 is a specific deacetylase for H3K9, see EC 2.3.1.286. It also deacetylates H3K56 and H3K18, as well as KAP1, CtIP, PGC-1alpha, TRF2, GCN5, SNF2H, and PKM2 2.3.1.B41 additional information SIRT6 is a specific deacetylase for H3K9, see EC 2.3.1.286. It also deacetylates H3K56 and H3K18, as well as KAP1, CtIP, PGC-1alpha, TRF2, GCN5, SNF2H, and PKM2, cf. EC 2.3.1.286 2.3.1.B41 additional information sirtuin6 performs H3K9 acetylation on histone H3, cf. EC 2.3.1.286 2.3.1.B41 NAD+ + [histone 3]-N6-palmitoyl-L-lysine - 2.3.1.B41 NAD+ + [histone H3 peptide]-N6-acetyl-L-lysine18 - 2.3.1.B41 NAD+ + [histone H3 peptide]-N6-acetyl-L-lysine9 - 2.3.1.B41 NAD+ + [histone H3]-N6-acetyl-L-lysine -