2.1.1.264	additional information	the bifunctional methyltransferase YcbY, i.e. RlmKL, adds the m7G2069 and m2G2445 modifications in Escherichia coli 23S rRNA, recognition of dual rRNA targets by YcbY	
2.1.1.264	additional information	the enzyme also catalyzes the N2-methylation of guanine2445 in 23S rRNA, RlmL activity, reaction of EC 2.1.1.173	
2.1.1.264	S-adenosyl-L-methionine + guanine2069 in 23S rRNA	-	
2.1.1.264	S-adenosyl-L-methionine + guanine2069 in 23S rRNA	RlmK activity in helix 74 of Escherichia coli 23S rRNA