2.1.1.208 S-adenosyl-L-methionine + uridine2479 in 23S rRNA AviRb from Streptomyces viridochromogenes methylates the 2'-O atom of uridine2479 of the 23S ribosomal RNA in Gram-positive bacteria and thus mediates resistance to the oligosaccharide antibiotic avilamycin 2.1.1.208 S-adenosyl-L-methionine + uridine2479 in 23S rRNA AviRb modifies the 2'-O-ribose position of nucleotide uridine2479 within helix 89