1.8.4.13	L-(-)-methionine S-oxide + NADPH	the enzyme is specific for the L-(-)-stereoisomer	
1.8.4.13	L-methionine (S)-sulfoxide + NADPH + H+	membrane-bound enzyme form Mem-R,S-Msr	
1.8.4.13	additional information	the enzyme protects cells against oxidative damage and plays a role in age-related misfunctions	
1.8.4.13	additional information	methionine sulfoxide reduction pathway, overview	
1.8.4.13	additional information	possible pathway, overview	
1.8.4.13	additional information	the enzyme might act in vivo on the free methionine sulfoxide substrate or on protein-bound methionine sulfoxide residues	
1.8.4.13	sulindac + NADPH	activation of a methionine sulfoxide-containing prodrug, activity with membrane-bound enzyme form Mem-R,S-Msr