1.4.4.2	glycine + H-protein-lipoyllysine	-	
1.4.4.2	glycine + H-protein-lipoyllysine	P-protein is the actual glycine-decarboxylating enzyme and uses pyridoxal 5'-phosphate as a cofactor. CO2 is released in the reaction and the residual aminomethyl group is bound to the oxidized lipoamide arm of H-protein	
1.4.4.2	glycine + lipoylprotein	-	
1.4.4.2	glycine + lipoylprotein	reaction is stimulated by lipoic acid which is a functional group of the H-protein	
1.4.4.2	glycine + lipoylprotein	glycine decarboxylation catalyzed by P-protein alone is extremely low	
1.4.4.2	glycine + lipoylprotein	lipoyl protein: H-protein, lipoamide can also act as acceptor	
1.4.4.2	glycine + [glycine-cleavage complex H protein]-N6-lipoyl-L-lysine	-	
1.4.4.2	additional information	nonketotic hyperglycinaemia is an autosomal recessive disorder of glycine metabolism caused by a deficiency in the mitochondrial glycine cleavage enzyme. The majority of cases are caused by mutations in the P-protein	
1.4.4.2	additional information	in transgenic potato plants with an antisense reduction in P-protein of GDC, the decrease in photorespiratory decarboxylation is compensated for by an increase in respiratory decarboxylation in the light