1.3.3.8 (S)-tetrahydroberberine + 2 O2 - 1.3.3.8 (S)-tetrahydroberberine + 2 O2 final step in berberine biosynthesis 1.3.3.8 (S)-tetrahydroberberine + 2 O2 7,14-dehydroberberinium as intermediate, protoberberine biosynthesis 1.3.3.8 additional information the recombinant enzyme expressed in transgenic Eschscholzia californica cells produces coptisine and dehydrocheilanthifoline from pathway intermediates cheilanthifoline and stylopine, overview