1.14.19.1 additional information biosynthesis of unsaturated fatty acids. Possible substrates: acyl-CoA, acyl-acyl-carrier and acyl chains of phospholipids. The substrate in vivo is saturated phospholipid 1.14.19.1 additional information rate limiting-step in the cellular synthesis of monounsaturated fatty acids mainly oleate and palmitoleate 1.14.19.1 additional information key enzyme in the synthesis of unsaturated fatty acyl-CoAs 1.14.19.1 additional information rate-limiting enzyme in the biosynthesis of monounsaturated fatty acids 1.14.19.1 additional information incorporation of the first unsaturation bond into saturated fatty acids 1.14.19.1 additional information long-chain polyunsaturated fatty acid biosynthetic pathway 1.14.19.1 additional information aging human orbitofrontal cortex includes decreasing of polyunsaturated fatty acid composition associates increases in lipogenic gene expression and stearoyl-CoA desaturase activity, overview 1.14.19.1 additional information Angus and Wagyu steers consuming high-roughage diets exhibit large differences in adipose tissue fatty acid composition, but there are no differences in terminal measures of CD activity or gene expression, overview 1.14.19.1 additional information decreased degradation of SCD is responsible for the increase in palmitoyl-CoA chain elongase activity in addition to increased transcription of SCD1 in the rats treated with clofibric acid, overview 1.14.19.1 additional information DesA3 is a membrane-bound stearoyl-CoA desaturase that works together with oxidoreductase Rv3230c, encoded by gene rv3230c, to produce oleic acid, an 55 essential constituent of mycobacterial membrane phospholipids and triglycerides