1.1.1.22	additional information	the transient capacity to dissociate and reorganize the hydrogen bond network at the interface between dimeric units is an important element of the normal catalytic cycle	
1.1.1.22	UDP-alpha-D-glucose + 2 NAD+ + H2O	-	
1.1.1.22	UDP-alpha-D-glucose + 2 NAD+ + H2O	the enzyme is involved in protein N-glycosylation	
1.1.1.22	UDP-glucose + 2 NAD+ + H2O	several different UDPGDH isoenzymes contribute to UDP-glucuronate and hence wall matrix biosynthesis in maize	
1.1.1.22	UDP-glucose + 2 NAD+ + H2O	the enzyme has a crucial role during development of Xenopus laevis. Silencing of UGDH decreases glycosaminoglycan synthesis causing severe embryonic malformations because of defective gastrulation process	
1.1.1.22	UDP-glucose + 2 NAD+ + H2O	UDPGDH-A activity has a more important role than UDPGDH-B in synthesis of UDP-glucuronate	
1.1.1.22	UDP-glucose + 2 NAD+ + H2O	-	
1.1.1.22	UDPglucose + NAD+ + H2O	-	
1.1.1.22	UDPglucose + NAD+ + H2O	first step of a branched pathway leading to plant cell-wall polysaccharides which contain glucuronic and galacturonic acids and the pentoses xylose, arabinose and apiose	
1.1.1.22	UDPglucose + NAD+ + H2O	delivers glucuronic acid for the formation of a antiphagocytic polysaccharide capsule that is required for virulence of pathogenic bacteria