6.2.1.4 ADP + phosphate + succinyl-CoA - 6.2.1.4 ATP + succinate + CoA - 6.2.1.4 GDP + phosphate + succinyl-CoA - 6.2.1.4 GDP + phosphate + succinyl-CoA GTP generated by the activation of succinyl-CoA synthetase could promote key functional roles in the mitochondrial metabolism leading to insulin secretion 6.2.1.4 GTP + succinate + CoA - 6.2.1.4 GTP + succinate + CoA succinyl CoA synthetase converts succinyl CoA to succinate in the Krebs cycle. The enzyme activity is reduced, when Helicobacter pylori transforms to the coccoid form, a viable but non-culturable form with reduced metabolic activity, overview 6.2.1.4 GTP + succinate + CoA SucCDAm is unspecific regarding ATP or GTP 6.2.1.4 GTP + succinate + CoA GTP is the preferred cosubstrate 6.2.1.4 GTP + succinate + CoA recycling of succinate to succinyl-CoA at the expense of GTP, involvement in heme biosynthesis 6.2.1.4 GTP + succinate + CoA not involved in citric acid cycle 6.2.1.4 GTP + succinate + CoA production of succinyl-CoA for ketone body metabolism and as a precursor for porphyrins 6.2.1.4 additional information the enzyme supports GTP-dependent anabolic processes 6.2.1.4 additional information succinate-CoA ligase catalyses the reversible conversion of succinyl-CoA and ADP or GDP to succinate and ATP or GTP, cf. ATP-specific succinate:CoA ligase, EC 6.2.1.5