5.6.1.2 ATP + H2O + a dynein associated with a microtubule at position n - 5.6.1.2 ATP + H2O + a dynein associated with a microtubule at position n cytoplasmic dynein heavy chain 2.2 is required for flagellar assembly and also participates in maintenance of promastigote cell shape. LmxDHC2.2 is not an essential gene 5.6.1.2 ATP + H2O + a dynein associated with a microtubule at position n cytoplasmic dynein is the sole motor for microtubule-based ER motility throughout the early stages of development 5.6.1.2 ATP + H2O + a dynein associated with a microtubule at position n dynactin and cytoplasmic dynein require each other for microtubule plus-end accumulation. The presence of cytoplasmic dynein is also important for the microtubule plus-end accumulation of NADF 5.6.1.2 ATP + H2O + a dynein associated with a microtubule at position n dynein has a dominant function in transporting kinetochore microtubule bundles (K fibers) to the centrosomes 5.6.1.2 ATP + H2O + a dynein associated with a microtubule at position n dynein is a primary motor for fast transport of mitochondria in Drosophila motor axons 5.6.1.2 ATP + H2O + a dynein associated with a microtubule at position n dynein is required directly for rotation of the centrosome/nucleus complex onto the proper embryonic axis, for correct chromosome congression, and for timely initiation of anaphase 5.6.1.2 ATP + H2O + a dynein associated with a microtubule at position n dynein is required for formation and early maintenance of the vegetal microtubule array 5.6.1.2 ATP + H2O + a dynein associated with a microtubule at position n dynein is required for microtubule-dependent movement of late endocytic vesicles 5.6.1.2 ATP + H2O + a dynein associated with a microtubule at position n dynein is required to prevent premature fast mass movement of cytoplasm (cytoplasmic streaming) 5.6.1.2 ATP + H2O + a dynein associated with a microtubule at position n dynein mediates retrograde neurofilament transport within axons and anterograde delivery of NFs from perikarya into axons 5.6.1.2 ATP + H2O + a dynein associated with a microtubule at position n dynein-dynactin, Asp, and KLP10A have complex interdependent functions in spindle pole focusing and centrosome attachment 5.6.1.2 ATP + H2O + a dynein associated with a microtubule at position n FK506-binding proteins 51 and 52 differentially regulate dynein interaction and nuclear translocation of the glucocorticoid receptor in mammalian cells 5.6.1.2 ATP + H2O + a dynein associated with a microtubule at position n kinesin I and cytoplasmic dynein orchestrate glucose-stimulated insulin-containing vesicle movements in clonal MIN6 beta-cells. The majority of transport of large dense-core vesicles in beta-cells is mediated by kinesin I, whilst dyneien probably contrtibutes to the recovery of vesicles after rapid kiss-and-run exocytosis 5.6.1.2 ATP + H2O + a dynein associated with a microtubule at position n Lmxdhc2.1 that encodes cytoplasmic dynein heavy chain 2.1 is an essentail gene in Leishmania 5.6.1.2 ATP + H2O + a dynein associated with a microtubule at position n model in which both the stalk and the extreme C terminus of the dynein heavy chain control the rate-limiting step of product release in the dynein enzymatic cycle through long range allosteric mechanisms 5.6.1.2 ATP + H2O + a dynein associated with a microtubule at position n the dynein light chain, Dlc1, is required preferentially for achiasmate segregation (segregation of homologous chromosomes in the absence of meiotic recombination), while the dynein heavy chain is required for meiotic chromosome segregation in both the presence and the absence of recombination 5.6.1.2 ATP + H2O + a dynein associated with a microtubule at position n the LC7 light chains of Chlamydomonas flagellar dyneins interact with components required for both motor assembly and regulation 5.6.1.2 ATP + H2O + a dynein associated with a microtubule at position n the majority of moving phagosomes are minus-end directed, the remainder moves towards microtubule plus-ends and a small subset moves bi-directionally. Minus-end movement showes pharmacological characteristics expected for dyneins, plus-end movement displayed pharmacological properties of kinesin 5.6.1.2 ATP + H2O + a dynein associated with a microtubule at position n cytoplasmic dynein is an AAA+ motor responsible for intracellular cargo transport and force generation along microtubules 5.6.1.2 ATP + H2O + a dynein associated with a microtubule at position n dynein is a motor protein that moves on microtubules using the energy of adenosine triphosphate hydrolysis 5.6.1.2 additional information cytoplasmic dynein may play structural and functional roles in the postsynaptic terminal 5.6.1.2 additional information dynein intermediate chain isoforms define dynein populations that are selectively recruited to transport distinct cargoes. Neurotrophin receptor tyrosine kinase B signaling endosomes are transported by cytoplasmic dynein containing the neuron-specific intermediate chain-1B isoform and not by dynein containing the ubiquitous intermediate chain-2C isoform. Organelles containing tyrosine kinase B also contain dynein with intermediate chain-1 but not intermediate chain-2 isoforms 5.6.1.2 additional information microtubules simultaneously accelerate the ATPase activity not only at the primary site but also at other site(s) in the dynein motor domain