5.3.3.12 dopachrome melanin biosynthesis 5.3.3.12 L-dopachrome - 5.3.3.12 L-dopachrome Dct isomerizes the intermediate dopachrome to 5,6-dihydroxyindole-2-carboxylic acid, DHICA, and influences the proportion of DHICA monomer incorporated into the 5,6-dihydroxyindole, DHI, polymer in eumelanin 5.3.3.12 additional information existence of a common mechanism underlying radio- and chemoresistance, which is mediated by the enzyme 5.3.3.12 additional information role of enzyme in cytoprotection by preventing the production of atoxic melanin precursor, 5,6-dihydroxyindole 5.3.3.12 additional information isoforms of enzyme may play a part in the normal pathway of melamin biosynthesis 5.3.3.12 additional information DCT interacts with melanin 5.3.3.12 additional information MIF is a 12 kDa protein with an enzymatic keto-enol tautomerase activityMIF is a homotrimeric multifunctional proinflammatory cytokine. Binding of MIF to its receptor, CD74, overview 5.3.3.12 additional information MIF is a homotrimeric multifunctional proinflammatory cytokine. Binding of MIF to its receptor, CD74, overview 5.3.3.12 additional information the MIF protein is multifunctional, exhibiting besides its L-dopachrome tautomerase activity, e.g. also phenylpyruvate tautomerase activity, EC 5.3.2.1, and thioredoxin-like function, or its cytokine function, overview