4.4.1.21	additional information	the enzyme is involved in one of the the quorum sensing systems that function in parallel to control the density-dependent expression of the luciferase structural operon luxCDABE. Each system is composed of a sensor, sensor I or sensor 2, and its cognate autoinducer, AI-1 or AI-2. LuxS has a role in the enzymatic synthesis of AI-2	
4.4.1.21	additional information	growth phase regulation of flaA expression in Helicobacter pylori is luxS-dependent	
4.4.1.21	additional information	LuxS is related on the one hand to down-regulation of competence, and on the other hand to attenuation of autolysis in cultures entering stationary phase. The impact of LuxS on competence, but not on autolysis, involves cel-cell communication	
4.4.1.21	additional information	the LuxS/AI-2 (autoinducer 2) system does not appear to contribute to the overall fitness of Staphylococcus aureus RN6390B during intracellular growth in epithelial cells	
4.4.1.21	additional information	LuxS catalyzes production of the AI-2 autoinducer molecule for a second quorum sensing system	
4.4.1.21	additional information	LuxS catalyzes the last step in the production of autoinducer-2	
4.4.1.21	additional information	LuxS is functional in the autoinducer-2-mediated quorum sensing and may regulate different behaviors including biofilm formation and virulence	
4.4.1.21	additional information	LuxS is involved in the activated methyl cycle and influences biofilm formation	
4.4.1.21	additional information	LuxS is required for normal biofilm development	
4.4.1.21	additional information	LuxS plays an important role in the regulation of motility and flagella biogenesis	
4.4.1.21	additional information	the LuxS quorum sensing system plays an important role in regulating the expression of virulence factors	
4.4.1.21	additional information	autoinducer 2 synthesis enzyme assay using Vibrio harveyi sensor strains, wild-type BB120 is a sensor mutant derived from BB120 and responds only to presence of AI-2, but not the other autoinducers from Vibrio harveyi	
4.4.1.21	S-(5-deoxy-D-ribos-5-yl)-L-homocysteine	-	
4.4.1.21	S-ribosylhomocysteine	-	
4.4.1.21	S-ribosylhomocysteine	enzyme is involved in synthesis of the autoinducer AI-2 that is an universal signal, which may be used by a variety of bacteria for communication among and between species and may be responsible for regulation of virulence genes in Escherichia coli O157:H7	
4.4.1.21	S-ribosylhomocysteine	key step in biosynthesis pathway of type II autoinducer AI-2	
4.4.1.21	S-ribosylhomocysteine	the enzyme is required for AI-2 synthesis, important metabolic function in recycling of S-adenosylhomocysteine