4.1.3.3	N-acetyl-D-mannosamine + pyruvate	reversible aldol condensation of pyruvate and N-acetyl-D-mannosamine	
4.1.3.3	N-acetyl-D-mannosamine + pyruvate	the enzyme catalyzes the retro-aldol cleavage of N-acetylneuraminic acid to form N-acetyl-D-mannosamine and pyruvate	
4.1.3.3	N-acetyl-D-neuraminic acid	-	
4.1.3.3	N-Acetylmannosamine + pyruvate	-	
4.1.3.3	N-Acetylmannosamine + pyruvate	N-acetylneuraminic acid is intermediate for colomic acid biosynthesis	
4.1.3.3	N-acetylneuraminate	-	
4.1.3.3	N-acetylneuraminate	100% activity	
4.1.3.3	N-Acetylneuraminic acid	regulation of sialic acid metabolism	
4.1.3.3	N-Acetylneuraminic acid	N-acetylneuraminate lyase plays important role in regulation of N-acetylneuraminic acid metabolism	
4.1.3.3	N-Acetylneuraminic acid	metabolized by pathogens parasitizing on mucous membranes